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COVID-19 Related News

Junior Desi
Member since: Jul 20

Posts: 1

According to French media Infotagion, the Covid-19 virus was reportedly produced in the US military facility in Fort Detrick, Frederick, Maryland, in the summer of 2019. Then it was spread to China accidentally or intentionally. Link

Post ID: 239169 02-07-20 22:17:37
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Full House
Senior Desi
Member since: Oct 12

Posts: 2642

Oxford, CanSino coronavirus vaccine trials show promising early results

Non-replicating viral vector vaccines induce immune response, show minor side effects, studies report

COVID-19 vaccine shows positive results in first phase of human trials 4 hours ago 8:42
Pharmaceutical company Astra Zeneca and scientists at Oxford University in the U.K. are seeing early signs of success in the first human trial for a COVID-19 vaccine. Phase 1 of the trial had more than 1,000 participants between the ages of 18 and 55. 8:42

Early results from human clinical trials of COVID-19 vaccines from the U.K. and China using similar technology suggest they are safe and induce an immune response in most patients, report two studies published Monday.

The two vaccines are being developed separately, one by AstraZeneca and Oxford University, the other by CanSino Biologics Inc. and China's military research unit.

The vaccine from AstraZeneca and Britain's University of Oxford, called AZD1222, has been described by the World Health Organization's chief scientist as the leading candidate in a global race to halt a pandemic that has claimed more than 600,000 lives.

It did not prompt any serious side effects and elicited antibody and T-cell immune responses, according to trial results published in The Lancet medical journal, with the strongest response seen in people who received two doses.

U.K. Prime Minister Boris Johnson, whose government has helped to fund the project, hailed the results as "very positive news."

However, the researchers cautioned the project was still at an early stage.

Vaccine trial results good news but there's a long way to go: WHO 5 hours ago 1:52
Dr. Michael Ryan, executive director of the World Health Organization's emergencies program, is encouraged by the most recent coronavirus vaccine data and says large-scale, real world trials will come next. 1:52 "There is still much work to be done before we can confirm if our vaccine will help manage the COVID-19 pandemic," vaccine developer Sarah Gilbert said.

"We still do not know how strong an immune response we need to provoke to effectively protect against SARS-CoV-2 infection," she said, adding researchers needed to learn more about COVID-19 and continue late stage trials, which have already commenced.

AstraZeneca shares surged 10 per cent, but then gave up most of those gains, to trade 1.2 per cent stronger on the day.

INTERACTIVE How close are we to a vaccine for COVID-19? AstraZeneca has signed agreements with governments around the world to supply the vaccine should it prove effective and gain regulatory approval. The company has said it will not seek to profit from the vaccine during the pandemic.

Adrian Hill, the director of Oxford University's Jenner Institute, said early projections that a million doses of the vaccine could be made by September could be an under-estimate, depending on how quickly late-stage trials can be completed. He added it remained possible that the vaccine could be in use by the end of the year.

Researchers said the vaccine caused minor side effects more frequently than a control group, but some of these could be reduced by taking paracetamol.

ONE million doses of potential COVID-19 vaccine by U.K. scientists to be made before proof it works
AZD1222 was developed by Oxford University and licensed to AstraZeneca, which has put it into large-scale, late-stage trials to test its efficacy. It has also already signed deals to produce and supply over 2 billion doses of the shot.

The new trial included 1,077 healthy adults aged 18-55 years with no history of COVID-19.

CanSino vaccine also shows promise, More than 150 possible vaccines are in various stages of development, with U.S. drug-maker Pfizer and China's CanSino Biologics also reporting positive responses for their candidates on Monday.

The COVID-19 vaccine developed by CanSino and China's military research unit was also shown to be safe and induced immune response in most of the recipients, researchers said on Monday.

The National Research Council of Canada announced in May that it would work with CanSino to try to develop its potential vaccine more quickly and to scale up the technology needed to produce enough of the candidate vaccine to protect Canadians.

China approves COVID-19 vaccine for military use, skips final phase of testing. The CanSino candidate, named Ad5-nCOV, is one of a handful of vaccines that have shown some promise in human testing and are gearing up for late-stage trials, along with projects involving Moderna Inc, BioNTech SE and Inovio Pharmaceuticals Inc.

While CanSino's vaccine has yet to start late-stage large-scale clinical trials to assess how well it works to prevent people from becoming infected, it has received the green light to be used in China's military.

The results from the mid-stage study, also published in the medical journal Lancet, supports the testing of the vaccine candidate in a large trial, the study authors said.

CanSino vaccine candidate to be used by Chinese military: China approves COVID-19 vaccine for military use. 20 days ago 8:43 .... A vaccine developed by a Chinese company in collaboration with the Canadian government will skip a final phase of testing and will be used on Chinese soldiers. "I really, really hope they're collecting detailed data," says infectious disease expert Dr. Isaac Bogoch. The vaccine by CanSino has been approved for human testing in Canada. 8:43

The vaccine candidate uses a virus called adenovirus to carry genetic material from the novel coronavirus' protein into the human body, a method also used by researchers at the University of Oxford and AstraZeneca for their vaccine candidate.

The immune responses elicited by the vaccine might be undermined if the inoculated person has already developed high-level adenovirus immunity from a previous infection, Chinese researchers said in a peer-reviewed paper.

Caution over early results. In an accompanying editorial, Naor Bar-Zeev and William Moss of the Johns Hopkins Bloomberg School of Public Health called both the Oxford and Chinese results "encouraging," but said further judgment should wait until the vaccine is tested on much bigger populations.

Bar-Zeev and Moss also called for any effective COVID-19 vaccine to be distributed equitably around the world.

"Global planning is underway, but should be underpinned and informed by specific local realities," they wrote. "Only this way can these very encouraging first early phase randomized trial results yield the global remedy for which we all yearn."

THE LATEST NEWS on Coronavirus: What's happening around the world: on Monday, 20th July 2020

Last week, American researchers announced that the first COVID-19 vaccine tested in the United States, boosted people's immune systems just as scientists had hoped and the shots will now enter the final phase of testing.

That vaccine, developed by the National Institutes of Health and Moderna, produced the molecules key to blocking infection in volunteers who got it, at levels comparable to people who survived a COVID-19 infection.

Federal government orders supplies to give two doses of COVID-19 vaccine when it's ready. The vaccine being developed by Pfizer also works to trigger a similar dual immune response as the Oxford shot.

Nearly two dozen potential vaccines are in various stages of human testing worldwide, with a handful entering necessary late-stage testing to prove effectiveness.

That is the best news that is in the making and as it happens.

Now we all will have to wait to get our immune system SHOT. Hope it will be soon. Sooner the better.


EDIT: 21st July 2020.

Last edited by: Full House on 21-07-20 00:48:08
Post ID: 239177 20-07-20 17:48:59
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